ExoticRx · exoticrx.com/drugs/desoxycorticosterone-pivalate
US brand names:Percorten-V, Zycortal
Desoxycorticosterone Pivalate is dosed at 2–2.2 mg/kg SC q25-30 days in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.383 (2026-08-01).. Verify against current literature before clinical use.
Pure mineralocorticoid that replaces aldosterone function, promoting sodium retention and potassium excretion in the distal renal tubule.
Requires concurrent glucocorticoid supplementation (prednisone). Dose and interval adjusted based on electrolytes. PU/PD if overdosed.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 2–2.2 mg/kg | q25-30 days | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.383 (2026-08-01). |
| Cat (Domestic) | SC | 2–2.2 mg/kg | q25 days | Weak | Reusch C. Hypoadrenocorticism. In: Ettinger S, Feldman E, eds. Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat. Vol 2. Philadelphia: WB Saunders; 2000:1488-1499. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.384 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.