ExoticRx · exoticrx.com/drugs/fenoldopam
US brand names:Corlopam
Fenoldopam is dosed at 0.1–0.8 mcg/kg/min IV Continuous IV infusion in dogs, per Kelly KL, Drobatz KJ, Foster JD. Effect of Fenoldopam Continuous Infusion on Glomerular Filtration Rate and Fractional Excretion of Sodium in Healthy Dogs. J Vet Intern Med. 2016;30(5):1655-1660. doi:10.1111/jvim.14522; Balakrishnan A, Drobatz KJ. Management of Urinary Tract Emergencies in Small Animals. Vet Clin North Am Small Anim Pract. 2013;43(4):843-867. doi:10.1016/j.cvsm.2013.03.013; Acierno MJ, Brown S, Coleman AE, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2018;32:1803-1822. doi:10.1111/jvim.15331 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.538 (2026-08-01).. Verify against current literature before clinical use.
Selective dopamine D1 receptor agonist causing renal and mesenteric vasodilation, reducing blood pressure while maintaining renal perfusion.
Continuous IV infusion only. Reflex tachycardia possible. Monitor blood pressure closely. May increase intraocular pressure.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Fenoldopam CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.8 mcg/kg/minContinuous IV infusion | Acute renal failure / hypertensive crisis | Moderate | Kelly KL, Drobatz KJ, Foster JD. Effect of Fenoldopam Continuous Infusion on Glomerular Filtration Rate and Fractional Excretion of Sodium in Healthy Dogs. J Vet Intern Med. 2016;30(5):1655-1660. doi:10.1111/jvim.14522; Balakrishnan A, Drobatz KJ. Management of Urinary Tract Emergencies in Small Animals. Vet Clin North Am Small Anim Pract. 2013;43(4):843-867. doi:10.1016/j.cvsm.2013.03.013; Acierno MJ, Brown S, Coleman AE, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2018;32:1803-1822. doi:10.1111/jvim.15331 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.538 (2026-08-01). |
| Cat (Domestic) |
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.8 mcg/kg/min | Continuous IV infusion | Moderate | Kelly KL, Drobatz KJ, Foster JD. Effect of Fenoldopam Continuous Infusion on Glomerular Filtration Rate and Fractional Excretion of Sodium in Healthy Dogs. J Vet Intern Med. 2016;30(5):1655-1660. doi:10.1111/jvim.14522; Balakrishnan A, Drobatz KJ. Management of Urinary Tract Emergencies in Small Animals. Vet Clin North Am Small Anim Pract. 2013;43(4):843-867. doi:10.1016/j.cvsm.2013.03.013; Acierno MJ, Brown S, Coleman AE, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2018;32:1803-1822. doi:10.1111/jvim.15331 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.538 (2026-08-01). |
| Cat (Domestic) | IV | 0.1–0.5 mcg/kg/min |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
| IV |
| 0.1–0.5 mcg/kg/minContinuous IV infusion |
| Acute renal failure / hypertensive crisis |
| Weak |
| Monaghan K, Nolan B, Labato M. Feline Acute Kidney Injury: Approach to diagnosis, treatment and prognosis. J Feline Med Surg. 2012;14(11):785-793. PMID: 23087004; Simmons JP, Wohl JS, Schwartz DD, Edwards HG, Wright JC. Diuretic effects of fenoldopam in healthy cats. J Vet Emerg Crit Care. 2006;16(2):96-103. doi:10.1111/j.1476-4431.2006.00176.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.538 (2026-08-01). |
Acute renal failure / hypertensive crisis
Acute renal failure / hypertensive crisis
| Continuous IV infusion |
| Weak |
| Monaghan K, Nolan B, Labato M. Feline Acute Kidney Injury: Approach to diagnosis, treatment and prognosis. J Feline Med Surg. 2012;14(11):785-793. PMID: 23087004; Simmons JP, Wohl JS, Schwartz DD, Edwards HG, Wright JC. Diuretic effects of fenoldopam in healthy cats. J Vet Emerg Crit Care. 2006;16(2):96-103. doi:10.1111/j.1476-4431.2006.00176.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.538 (2026-08-01). |