ExoticRx · exoticrx.com/drugs/fludrocortisone
US brand names:Florinef
Fludrocortisone is dosed at 0.05–0.1 mg/kg PO q24h or divided q12h in ferrets, per Shoemaker NJ, van Zeeland YR.A, Quesenberry KE, et al. Endocrine diseases of ferrets Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:77-91. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.949 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.8 (Endocrine and Reproductive Disease Agents Used in Ferrets). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350. Verify against current literature before clinical use.
Synthetic corticosteroid with potent mineralocorticoid activity promoting sodium retention and potassium excretion at the distal tubule. Also has glucocorticoid activity.
Monitor electrolytes (Na/K ratio). Dose escalation over time is common. May cause PU/PD, weight gain, hypertension. Used for hypoadrenocorticism (Addison's).
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Ferret drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 3 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 0.01–0.02 mg/kg | q12-24h | Weak | BSAVA Small Animal Formulary 10th Ed, Part A, printed p.169 (corpus page 185), Fludrocortisone > DOSES > Cats — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
| Dog (Domestic) | PO | 0.01–0.02 mg/kg | q12-24h | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted), printed p.536 (corpus page 563), Fludrocortisone > Dosages > DOGS — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.