ExoticRx · exoticrx.com/drugs/fludrocortisone
US brand names:Florinef
Fludrocortisone is dosed at 0.01–0.02 mg/kg PO q12-24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed, printed p.536 (corpus page 563), Fludrocortisone > Dosages > DOGS. Verify against current literature before clinical use.
Synthetic corticosteroid with potent mineralocorticoid activity promoting sodium retention and potassium excretion at the distal tubule. Also has glucocorticoid activity.
Monitor electrolytes (Na/K ratio). Dose escalation over time is common. May cause PU/PD, weight gain, hypertension. Used for hypoadrenocorticism (Addison's).
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.01–0.02 mg/kg | q12-24h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed, printed p.536 (corpus page 563), Fludrocortisone > Dosages > DOGS |
| Cat (Domestic) | PO | 0.01–0.02 mg/kg | q12-24h | Weak | BSAVA Small Animal Formulary 10th Ed, Part A, printed p.169 (corpus page 185), Fludrocortisone > DOSES > Cats |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.