ExoticRx · exoticrx.com/drugs/gentamicin-ophthalmic
US brand names:Gentocin Ophthalmic, Genoptic
Aminoglycoside binding 30S ribosomal subunit. Bactericidal concentration-dependent. Excellent gram-negative coverage including Pseudomonas.
Corneal epithelial toxicity with prolonged use (>7-10 days). Good for gram-negative ocular infections. Can be used with corneal ulcers. Resistance increasing.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Corneal epithelial toxicity with prolonged use | q4-6h, may increase to q30-60min if needed | Strong | Plumb's Veterinary Drug Handbook, 10th ed (held), Gentamicin Ophthalmic monograph, Dosages, printed p.1370-1371 (corpus PDF p.1397-1398). [CORRECTED - the 2026-08-12 note asserting no gentamicin ophthalmic monograph exists in the held 10th ed is FALSE. It exists as a standalone monograph between Gatifloxacin Ophthalmic and Hydrocortisone Ophthalmic and carries a Dosages block. The earlier locator pointed at printed p.1429 Gentamicin Topical, a different entry.] Add - "Gentamicin should not be used if a full-thickness corneal wound is present, as gentamicin is toxic […]" |
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