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Gonadorelin (GnRH) for Horse

Equine · Equus caballus · typical adult weight 350.00–700.00 kg

Gonadorelin (GnRH) is used in horse for Ovulation induction, ovarian cysts. Routes documented in horse: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Gonadorelin (GnRH) in horse, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Factrel, Fertagyl, Cystorelin, OvaCyst

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV50–100 mcg total doseAs neededSingle or repeated dosesOvulation induction, ovarian cystsModeratePlumb's Veterinary Drug Handbook

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Mechanism of action

Synthetic gonadotropin-releasing hormone (GnRH) that stimulates release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. Causes ovulation or luteinization of follicles.

Side effects & warnings

Used in timed AI protocols (Ovsynch, CoSynch) in cattle. No withdrawal period required. Response depends on stage of estrous cycle and presence of a dominant follicle.

Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Endocrine drugs with horse dosing

Gonadorelin (GnRH) dosing in other species

Why a species-specific page? Gonadorelin (GnRH) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.