ExoticRx · exoticrx.com/drugs/hydrogen-peroxide-3-emetic
US brand names:H2O2 3% USP
Local irritant that stimulates pharyngeal and gastric sensory neurons triggering the emetic reflex via vagal afferents to the vomiting center.
Dogs ONLY — do NOT use in cats (severe hemorrhagic gastritis). Use only 3% solution. May repeat once. Do not use if caustic or sharp object ingested. Maximum 45ml per dose.
Species references:All Dog (Domestic) drugsAll Guinea Pig drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 ml/kg | Single dose; repeat x1 if no emesis | Strong | Khan SA, McLean MK, Slater M, Hansen S, Zawistowski S. Effectiveness and adverse effects of the use of apomorphine and 3% hydrogen peroxide solution to induce emesis in dogs. Javma-Journal of the American Veterinary Medical Association. Nov 2012;241(9):1179-1184. doi:10.2460/javma.241.9.1179; Peterson ME, Talcott PA. Small Animal Toxicology, 3rd Ed. Saunders; 2013. doi:10.1016/c2010-0-67099-4; Lee J. Approach to Drug Overdose. In: Silverstein DC, Hopper K, eds. Small Animal Critical Care Medicine. 2nd ed. Elsevier-Saunders; 2015:385-389:chap 74. doi:10.1016/b978-1-4557-0306-7.00074-x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.646 (2026-08-01). |
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