ExoticRx · exoticrx.com/drugs/ibrexafungerp
US brand names:Brexafemme
Inhibits beta-1,3-D-glucan synthase at a site distinct from echinocandins. First oral glucan synthase inhibitor. Active against azole- and echinocandin-resistant Candida.
GI upset. Teratogenic — contraindicated in pregnancy. CYP3A4 interactions. Novel mechanism. No veterinary data.
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