Amphibian · Salamandra salamandra · typical adult weight 0.02–0.04 kg
Itraconazole is dosed at 0.01 % itraconazole solution (= 100 ug/mL) bath Immersion (bath) daily for at least 11 consecutive days in fire salamanders, per Plewnia A, Lotters S, Veith M, Peters M, Boning P. Successful Drug-Mediated Host Clearance of Batrachochytrium salamandrivorans. Emerg Infect Dis. 2023;29(2):411-414. Itraconazole is used in fire salamanders for Chytridiomycosis caused by Batrachochytrium salamandrivorans (Bsal, salamander plague). Routes documented in fire salamanders: Immersion (bath). A typical adult fire salamander weighs 0.02–0.04 kg. ExoticRx lists 1 cited dose rule for Itraconazole in fire salamanders, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sporanox, Itrafungol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Immersion (bath) | 0.01 % itraconazole solution (= 100 ug/mL) bath | daily for at least 11 consecutive days | Contact time 10 minutes per bath, once daily, for MORE than 11 consecutive days - treatment ran to negative swabs, so 11 days is a floor and not a fixed course. Prepared as Sempera Liquid 10 mg/mL diluted 1:100 in distilled water. Animals were swabbed daily before bathing, transferred daily to disinfected enclosures, and monitored for more than 8 weeks after treatment ended. | Chytridiomycosis caused by Batrachochytrium salamandrivorans (Bsal, salamander plague) | Weak | Plewnia A, Lotters S, Veith M, Peters M, Boning P. Successful Drug-Mediated Host Clearance of Batrachochytrium salamandrivorans. Emerg Infect Dis. 2023;29(2):411-414. doi:10.3201/eid2902.221162 https://pmc.ncbi.nlm.nih.gov/articles/PMC9881767/ |
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Enter your fire salamander's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Inhibits fungal 14-alpha-demethylase, blocking ergosterol synthesis. Lipophilic with high tissue concentrations.
Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Species-specific contraindications and adverse-reaction reports for fire salamanders may differ from canine / feline reference data — consult the primary citations listed with each rule.
Itraconazole dose range in fire salamanders, with cited source references: Immersion (bath) 0.01 % itraconazole solution (= 100 ug/mL) bath daily for at least 11 consecutive days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Itraconazole in fire salamanders: Immersion (bath).
Cited course lengths for Itraconazole in fire salamanders include: Contact time 10 minutes per bath, once daily, for MORE than 11 consecutive days - treatment ran to negative swabs, so 11 days is a floor and not a fixed course. Prepared as Sempera Liquid 10 mg/mL diluted 1:100 in distilled water. Animals were swabbed daily before bathing, transferred daily to disinfected enclosures, and monitored for more than 8 weeks after treatment ended.. Duration depends on the indication — match it to the specific dose rule in the table above.
Itraconazole is indicated in fire salamanders for: Chytridiomycosis caused by Batrachochytrium salamandrivorans (Bsal, salamander plague).
These are general warnings for Itraconazole across species; consult the fire salamander dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Why a species-specific page? Itraconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in fire salamanders — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.