ExoticRx · exoticrx.com/drugs/ivabradine
US brand names:Corlanor
Ivabradine is dosed at 1 mg/kg PO q12h in dogs, per Pirintr P, Limprasutr V, Saengklub N, et al. Effects of ivabradine on heart rate and left ventricular function in dogs with asymptomatic degenerative mitral valve disease. Exp Anim. 2018. PMID:29760343 — oral doses of 0.5, 1.0 and 2.0 mg/kg were studied; "A single oral ivabradine administration at a dose of 1.0 mg/kg is suitable for dogs with […]" Retrieved 2026-08-05. — https://pubmed.ncbi.nlm.nih.gov/29760343/. Verify against current literature before clinical use.
Selectively inhibits the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel (funny current, If) in the sinoatrial node, reducing heart rate without affecting contractility.
Bradycardia risk. Avoid in atrial fibrillation or severe hepatic impairment. Emerging veterinary interest for feline hypertrophic cardiomyopathy.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1 mg/kg | q12h | Moderate | Pirintr P, Limprasutr V, Saengklub N, et al. Effects of ivabradine on heart rate and left ventricular function in dogs with asymptomatic degenerative mitral valve disease. Exp Anim. 2018. PMID:29760343 — oral doses of 0.5, 1.0 and 2.0 mg/kg were studied; "A single oral ivabradine administration at a dose of 1.0 mg/kg is suitable for dogs with […]" Retrieved 2026-08-05. — https://pubmed.ncbi.nlm.nih.gov/29760343/ |
| Cat (Domestic) | PO | 0.3 mg/kg | q12h | Weak | Blass KA, Schober KE, Li X, Scansen BA, Bonagura JD. Acute effects of ivabradine on dynamic obstruction of the left ventricular outflow tract in cats with preclinical hypertrophic cardiomyopathy. J Vet Intern Med. 2014;28(3):838-846. — ivabradine 0.3 mg/kg PO, single dose. Retrieved 2026-08-05. — |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.