Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Ivermectin is used in horse for GI strongyles, bots, pinworms. Routes documented in horse: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Ivermectin in horse, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Ivomec, Heartgard
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.2 mg/kg | single dose | GI strongyles, bots, pinworms | Strong | FDA NADA Label |
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Potentiates glutamate-gated chloride channels in invertebrate nerve and muscle cells, causing paralysis and death of parasites.
TOXIC to MDR1-mutant dogs (Collies, Shelties, Aussies) at elevated doses. DO NOT use in chelonians (turtles/tortoises). Narrow safety margin in some species. Test MDR1 status before use in herding breeds.
Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Ivermectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.