Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lifitegrast Ophthalmic is used in dog for Keratoconjunctivitis sicca (KCS). Routes documented in dog: Ophthalmic. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lifitegrast Ophthalmic in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Xiidra
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Ophthalmic | 0 mg/kg | 1 drop affected eye(s) q12h | Chronic use; reassess at 6-8 weeks | Keratoconjunctivitis sicca (KCS) | Weak | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Blocks binding of lymphocyte function-associated antigen 1 (LFA-1) to intercellular adhesion molecule 1 (ICAM-1), inhibiting T-cell activation and inflammatory cytokine release.
Used for keratoconjunctivitis sicca (dry eye). Common side effects include dysgeusia and instillation site irritation. Limited veterinary data.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Lifitegrast Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.