ExoticRx · exoticrx.com/drugs/linaclotide
Linzess
Guanylate cyclase-C agonist that increases cyclic GMP, stimulating intestinal chloride and bicarbonate secretion, accelerating transit and reducing visceral pain.
Diarrhea is most common side effect. Not absorbed systemically. Minimal veterinary data — experimental use only.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.003–0.01 mg/kg | q24h | Extrapolated | Veterinary Gastroenterology Literature Review |
| Cat (Domestic) | PO | 0.003–0.01 mg/kg | q24h | Extrapolated | Veterinary Gastroenterology Literature Review |
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