ExoticRx · exoticrx.com/drugs/losartan
US brand names:Cozaar
Losartan is dosed at 0.5–1 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Losartan, Dosages: DOGS, IRIS consensus (corpus p.809); corroborated by Papich Saunders Handbook of Veterinary Drugs, Losartan, Small Animal Dosage (corpus p.489) — LOCATOR CONVENTION 2026-08-07: the bare 'p.809' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.782; verified by finding the drug named there. If you are holding the book, turn to p.782. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Verify against current literature before clinical use.
Selectively blocks angiotensin II type 1 (AT1) receptors. Reduces aldosterone secretion, vasoconstriction, and cardiac remodeling without affecting bradykinin.
Limited veterinary data. Alternative to ACE inhibitors for patients with ACEi-related side effects. Hyperkalemia risk. Monitor renal function.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1 mg/kg | q24h | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Losartan, Dosages: DOGS, IRIS consensus (corpus p.809); corroborated by Papich Saunders Handbook of Veterinary Drugs, Losartan, Small Animal Dosage (corpus p.489) — LOCATOR CONVENTION 2026-08-07: the bare 'p.809' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.782; verified by finding the drug named there. If you are holding the book, turn to p.782. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.