Cat · Felis catus · typical adult weight 2.50–7.00 kg
Megestrol Acetate is used in cat for Behavioral (spraying)/Estrus suppression. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Megestrol Acetate in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Ovaban, Megace
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2.5–5 mg/kg | q24h for 5 days, then q7d | 5-day induction, then weekly maintenance; use shortest course possible | Behavioral (spraying)/Estrus suppression | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Absolute dose ceiling, regardless of body weight: 20 mg total (PO).
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Synthetic progestational agent that suppresses estrus and gonadotropin release. Also has glucocorticoid activity and appetite-stimulating effects.
Significant side effects: pyometra, mammary tumors, diabetes mellitus, adrenal suppression. Use only when surgical sterilization not possible. Short courses only.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Megestrol Acetate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.