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Proligestone for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Proligestone is used in cat for Estrus suppression. Routes documented in cat: SC. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Proligestone in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Delvosteron, Covinan

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
SC10–33 mg/kgSingle injection; repeat q4-5 monthsSingle depot injection; repeat every 4-5 monthsEstrus suppressionModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

14-alpha,17-alpha-progesterone derivative that suppresses estrus by inhibiting gonadotropin release. Long-acting depot injection.

Side effects & warnings

Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Reproductive drugs with cat dosing

Proligestone dosing in other species

Why a species-specific page? Proligestone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.