ExoticRx · exoticrx.com/drugs/melatonin
US brand names:Melatonin
Melatonin is dosed at 0.5–1 mg/animal (total dose, NOT mg/kg) PO q24h prn in ferrets, per Ramer JC, Benson KG, Morrisey JK, et al. Effects of melatonin administration on the clinical course of adrenocortical disease in domestic ferrets. J Am Vet Med Assoc. 2006;229:1743-1748. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.950 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.8 (Endocrine and Reproductive Disease Agents Used in Ferrets). Verify against current literature before clinical use.
Activates MT1 and MT2 receptors. Modulates circadian rhythms, reproductive cyclicity, and coat growth. Anti-adrenal effects via inhibition of cortisol synthesis.
Used for alopecia X (hair loss), Cushing's disease adjunct, and reproductive management in ferrets. Avoid xylitol-containing products. Generally very safe.
Species references:All Dog (Domestic) drugsAll Ferret drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 3–6 mg per dog | q8-12h | Weak | Chapter 9 - Hereditary, Congenital, and Acquired Alopecias. In: Hnilica KA, Patterson AP, eds. Small Animal Dermatology (Fourth Edition). W.B. Saunders; 2017:302-352. — Plumb's 10th ed printed p.823, Melatonin monograph spanning p.823-824.Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.