ExoticRx · exoticrx.com/drugs/memantine
US brand names:Namenda
Memantine is dosed at 0.3–1 mg/kg PO q12h in dogs, per Schneider, B.M., Dodman, N.H., and Maranda, L. (2009b). Use of memantine in treatment of canine compulsive disorders. Journal of Veterinary Behavior: Clinical Applications and Research 4 (3): 118-126. — Verified against Veterinary Psychopharmacology (Crowell-Davis), 2nd Ed, p.206 (2026-08-01).. Verify against current literature before clinical use.
Non-competitive NMDA glutamate receptor antagonist. Blocks pathological sustained NMDA activation while allowing normal synaptic transmission.
Limited veterinary data. Investigated for cognitive dysfunction syndrome in dogs. May cause restlessness, GI upset. Renal elimination — adjust in renal disease.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.3–1 mg/kg | q12h | Weak | Schneider, B.M., Dodman, N.H., and Maranda, L. (2009b). Use of memantine in treatment of canine compulsive disorders. Journal of Veterinary Behavior: Clinical Applications and Research 4 (3): 118-126. — Verified against Veterinary Psychopharmacology (Crowell-Davis), 2nd Ed, p.206 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.