ExoticRx · exoticrx.com/drugs/n-butylscopolammonium-bromide
Buscopan, Buscopan Compositum, Hyoscine
Quaternary ammonium anticholinergic that blocks muscarinic receptors on GI smooth muscle, reducing spasm and motility. Does not cross the blood-brain barrier, limiting central side effects.
Tachycardia is common and expected. Transient ileus possible. Contraindicated in mechanical GI obstruction. Used primarily in horses for colic. Monitor heart rate during administration.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.3–0.5 mg/kg | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
| Cat (Domestic) | IV | 0.3–0.5 mg/kg | q8-12h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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