ExoticRx · exoticrx.com/drugs/n-butylscopolammonium-bromide
US brand names:Buscopan, Buscopan Compositum, Hyoscine
Also known as: Hyoscine Butylbromide, Butylscopolamine, Buscopan
N-Butylscopolammonium Bromide is dosed at 0.3–0.5 mg/kg IV q8-12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database. Verify against current literature before clinical use.
Quaternary ammonium anticholinergic that blocks muscarinic receptors on GI smooth muscle, reducing spasm and motility. Does not cross the blood-brain barrier, limiting central side effects.
Tachycardia is common and expected. Transient ileus possible. Contraindicated in mechanical GI obstruction. Used primarily in horses for colic. Monitor heart rate during administration.
Species references:All Dog (Domestic) drugs
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