ExoticRx · exoticrx.com/drugs/naltrexone
Trexonil, ReVia
Long-acting competitive opioid receptor antagonist. Oral bioavailability and longer half-life than naloxone.
Used for stereotypic/compulsive behaviors (self-mutilation, cribbing in horses). Hepatotoxicity at high doses. Blocks endogenous opioid reward pathways.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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