ExoticRx · exoticrx.com/drugs/nitroglycerin
US brand names:Nitro-Bid, Nitrostat, Nitrol, Glyceryl Trinitrate
Releases nitric oxide causing smooth muscle relaxation. Predominantly venodilator reducing preload. Also dilates coronary arteries.
Apply to hairless skin with gloves. Tolerance develops rapidly with continuous use — use 10-12 hour nitrate-free intervals. Monitor blood pressure.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Topical | Apply to inner pinna or groin | 0.5-2 inch (1.3-5 cm) strip q12h on hairless skin | Moderate | Keene BW, Atkins CE, Bonagura JD, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med. 2019;33:1127-1140. doi:10.1111/jvim.15488 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.966 (2026-08-01). |
| Dog (Domestic) | Topical | Apply 0.5-2 inch (1.3-5 cm) strip to hairless skin (ear pinna, groin) | q12h | Moderate | Keene BW, Atkins CE, Bonagura JD, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med. 2019;33:1127-1140. doi:10.1111/jvim.15488 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.966 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.