ExoticRx · exoticrx.com/drugs/nortriptyline
US brand names:Pamelor
Nortriptyline is dosed at 1–2 mg/kg PO q12h in dogs, per Veterinary Psychopharmacology (Crowell-Davis), 2nd Ed, p.233. Verify against current literature before clinical use.
Active metabolite of amitriptyline. Inhibits norepinephrine reuptake preferentially over serotonin. Anticholinergic, antihistaminic, and alpha-adrenergic blocking properties.
Cardiac toxicity risk — monitor ECG in susceptible species. Anticholinergic effects: dry mouth, urinary retention, constipation. Do not combine with MAOIs.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q12h | Weak | Veterinary Psychopharmacology (Crowell-Davis), 2nd Ed, p.233Compilation only — we have not located an independent source that prints this figure. |
| Cat (Domestic) | PO | 0.5–1 mg/kg | q12h | Weak | Veterinary Psychopharmacology (Crowell-Davis), 2nd Ed, p.233Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.