ExoticRx · exoticrx.com/drugs/novobiocin
US brand names:Albamycin
Novobiocin is dosed at 10–22 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Inhibits bacterial DNA gyrase B subunit, blocking ATPase activity. Active primarily against gram-positive bacteria especially staphylococci.
Often used in combination. GI upset common. Hepatotoxicity reported. Resistance develops rapidly with monotherapy.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–22 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.