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Omeprazole for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Omeprazole is used in guinea pig for Gastric ulceration. Routes documented in guinea pig: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Omeprazole in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Prilosec, GastroGard

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.5–1 mg/kgq24h7-14 daysGastric ulcerationExtrapolatedCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Irreversibly inhibits H+/K+-ATPase (proton pump) on parietal cells, providing potent and prolonged gastric acid suppression.

Side effects & warnings

Must not be crushed (enteric-coated). Takes 3-5 days for full effect. Long-term use may affect calcium/magnesium absorption. Interacts with drugs requiring acid pH for absorption.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Gastrointestinal drugs with guinea pig dosing

Omeprazole dosing in other species

Why a species-specific page? Omeprazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.