What is Orbifloxacin used for?

Orbifloxacin is indicated for: Bacterial infection (fluoroquinolone), Skin infections, UTI.

Which species have cited Orbifloxacin dosing data?

Orbifloxacin dosing in the ExoticRx formulary covers 3 species: African Pygmy Hedgehog, Cat (Domestic), Dog (Domestic).

Is Orbifloxacin a controlled substance?

Orbifloxacin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

What are the side effects of Orbifloxacin?

Reported side effects, adverse reactions, and contraindications for Orbifloxacin: Avoid in growing animals (cartilage damage). Use cautiously in cats. May lower seizure threshold. Concentration-dependent killing.

Orbifloxacin

US brand names:Orbax

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Orbifloxacin is dosed at 10–20 mg/kg PO q12-24h in african pygmy hedgehogs, per 27. Helmer PJ, Carpenter JW. Hedgehogs. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:443-458. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.734 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.1 (Antimicrobial Agents Used in Hedgehogs). Verify against current literature before clinical use.

Drug Class

Antibiotic

Routes

Indications

Bacterial infection (fluoroquinolone)Skin infectionsUTI

Mechanism of Action

Inhibits bacterial DNA gyrase and topoisomerase IV. Veterinary-specific fluoroquinolone with concentration-dependent killing.

Side effects & warnings

Avoid in growing animals (cartilage damage). Use cautiously in cats. May lower seizure threshold. Concentration-dependent killing.

Species with Orbifloxacin dosing data (3 dose rules)

African Pygmy Hedgehog Cat (Domestic)Dog (Domestic)

Species references:All African Pygmy Hedgehog drugs All Cat (Domestic) drugs All Dog (Domestic) drugs

Evidence levels across 3 dose rules

Strong×2Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Sample dosing (2 of 3 cited rules)

A dog/cat sample is shown here. Cited dosing for all 3 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	2.5–7.5 mg/kg	q24h	Strong	ORBAX- orbifloxacin tablet, coated [package insert]. Summit, NJ: Merck Animal Health; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a4cabca-caa0-4df3-bc46-963f0804b54a — Plumb's 10th ed printed p.959, Orbifloxacin monograph spanning p.958-959.
Cat (Domestic)	PO	2.5–7.5 mg/kg	q24h	Strong	ORBAX- orbifloxacin tablet, coated [package insert]. Summit, NJ: Merck Animal Health; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a4cabca-caa0-4df3-bc46-963f0804b54a — Plumb's 10th ed printed p.959, Orbifloxacin monograph spanning p.958-959.

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Backed by 2 published sourcesShow

· 27. Helmer PJ, Carpenter JW. Hedgehogs. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:443-458. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.734 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.1 (Antimicrobial Agents Used in Hedgehogs).
· ORBAX- orbifloxacin tablet, coated [package insert]. Summit, NJ: Merck Animal Health; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a4cabca-caa0-4df3-bc46-963f0804b54a — Plumb's 10th ed printed p.959, Orbifloxacin monograph spanning p.958-959.

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