ExoticRx · exoticrx.com/drugs/orbifloxacin
US brand names:Orbax
Orbifloxacin is dosed at 2.5–7.5 mg/kg PO q24h in dogs, per ORBAX- orbifloxacin tablet, coated [package insert]. Summit, NJ: Merck Animal Health; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a4cabca-caa0-4df3-bc46-963f0804b54a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.986 (2026-08-01).. Verify against current literature before clinical use.
Inhibits bacterial DNA gyrase and topoisomerase IV. Veterinary-specific fluoroquinolone with concentration-dependent killing.
Avoid in growing animals (cartilage damage). Use cautiously in cats. May lower seizure threshold. Concentration-dependent killing.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2.5–7.5 mg/kg | q24h | Strong | ORBAX- orbifloxacin tablet, coated [package insert]. Summit, NJ: Merck Animal Health; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a4cabca-caa0-4df3-bc46-963f0804b54a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.986 (2026-08-01). |
| Cat (Domestic) | PO | 2.5–7.5 mg/kg | q24h | Strong | ORBAX- orbifloxacin tablet, coated [package insert]. Summit, NJ: Merck Animal Health; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a4cabca-caa0-4df3-bc46-963f0804b54a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.986 (2026-08-01). |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.