ExoticRx · exoticrx.com/drugs/phenobarbital-compounded-oral
US brand names:Compounded Phenobarbital Solution
Phenobarbital Compounded Oral is dosed at 1–2 mg/kg PO q12h in cats, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1036 (2026-08-01). — Plumb's 10th ed (held) printed p.1006, Phenobarbital monograph spanning p.1006-1010; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Enhances GABA-A receptor activity and reduces glutamate excitability. Long-acting anticonvulsant. Compounded for precise small-animal dosing.
Controlled substance (CIV). Hepatotoxic with chronic use — monitor liver values. Compounded formulation allows precise small-patient dosing. Verify potency testing with pharmacy.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Controlled substance in the US
Controlled-drug status and schedules differ by country — check your local scheduling rules.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 1–2 mg/kg | q12h | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1036 (2026-08-01). — Plumb's 10th ed (held) printed p.1006, Phenobarbital monograph spanning p.1006-1010; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Dog (Domestic) | PO | 2.5–5 mg/kg | q12h | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), p.626 (PDF 654), Small Animal Dosage — Dogs, and Formulations (compounded 10 mg/mL oral suspension) — LOCATOR CONVENTION 2026-08-07: 'p.626' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.