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Phenoxybenzamine Ophthalmic

Compounded Phenoxybenzamine Ophthalmic

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Ophthalmic

Routes

Ophthalmic

Indications

Intraoperative pupil maintenancePre-operative mydriasis (cataract surgery)

Mechanism of Action

Irreversible alpha-adrenergic antagonist that causes smooth muscle relaxation of the iris dilator, preventing miosis. Used to facilitate mydriasis in heavily pigmented irises.

Side effects & warnings

Must be compounded. Used pre-operatively for cataract surgery in dogs with dark irises. Irreversible binding — effects last 24-48 hours. Local irritation possible.

Species with Phenoxybenzamine Ophthalmic dosing data (2 dose rules)

Dog (Domestic)

Species references:All Dog (Domestic) drugs

Evidence levels across 2 dose rules

Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Gelatt KN, Veterinary Ophthalmology, 6th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Ophthalmic0 mg/kg1 drop q8h starting 24h before surgeryModerateGelatt KN, Veterinary Ophthalmology, 6th Ed
Dog (Domestic)Ophthalmic0 mg/kg1 drop pre-operatively, repeat if neededModerateGelatt KN, Veterinary Ophthalmology, 6th Ed

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Other formulations of Phenoxybenzamine

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Calculate Dosage for Phenoxybenzamine Ophthalmic