Ponazuril (Livestock) for Cattle
Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Ponazuril (Livestock) is used in cattle for Coccidiosis in calves. Routes documented in cattle: PO. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Ponazuril (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Toltrazuril Sulfone
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 20 mg/kg | Once | Single dose | Coccidiosis in calves | Moderate | Plumb's Veterinary Drug Handbook |
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Active metabolite of toltrazuril. Inhibits mitochondrial enzyme systems in coccidia, disrupting nuclear division and mitochondrial function in all intracellular stages.
Side effects & warnings
Extra-label use in livestock. Primarily used in calves and lambs for coccidiosis treatment and prevention. Long half-life allows single-dose protocols.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antiparasitic drugs with cattle dosing
Ponazuril (Livestock) dosing in other species
Why a species-specific page? Ponazuril (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.