Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Ponazuril (Livestock) is dosed at 20 mg/kg PO Once in cattle, per Riviere JE, Papich MG, eds. Veterinary Pharmacology and Therapeutics, Ch.42 Antiprotozoan Drugs, summary table (corpus p.1154): Neosporosis, Neospora caninum, Cattle — 'Ponazuril: 20 mg/kg PO q24h for 6 days'. Ponazuril (Livestock) is used in cattle for Coccidiosis in calves. Routes documented in cattle: PO. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Ponazuril (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Toltrazuril Sulfone
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 20 mg/kg | Once | Single dose | Coccidiosis in calves | Moderate | Riviere JE, Papich MG, eds. Veterinary Pharmacology and Therapeutics, Ch.42 Antiprotozoan Drugs, summary table (corpus p.1154): Neosporosis, Neospora caninum, Cattle — 'Ponazuril: 20 mg/kg PO q24h for 6 days' |
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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Active metabolite of toltrazuril. Inhibits mitochondrial enzyme systems in coccidia, disrupting nuclear division and mitochondrial function in all intracellular stages.
Extra-label use in livestock. Primarily used in calves and lambs for coccidiosis treatment and prevention. Long half-life allows single-dose protocols.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ponazuril (Livestock) dose range in cattle, with cited source references: PO 20 mg/kg Once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ponazuril (Livestock) in cattle: PO.
Cited course lengths for Ponazuril (Livestock) in cattle include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Ponazuril (Livestock) is indicated in cattle for: Coccidiosis in calves.
These are general warnings for Ponazuril (Livestock) across species; consult the cattle dosing table above for species-specific guidance. Extra-label use in livestock. Primarily used in calves and lambs for coccidiosis treatment and prevention. Long half-life allows single-dose protocols.
Why a species-specific page? Ponazuril (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.