ExoticRx · exoticrx.com/drugs/pradofloxacin
US brand names:Veraflox
Pradofloxacin is dosed at 5–10 mg/kg PO q24h in cats, per Dowers KL, Tasker S, Radecki SV, Lappin MR. Use of pradofloxacin to treat experimentally induced Mycoplasma hemofelis infection in cats. Am J Vet Res. 2009;70(1):105-111. doi:10.2460/ajvr.70.1.105 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1077 (2026-08-01). — Plumb's 10th ed (held) printed p.1050, Pradofloxacin monograph spanning p.1048-1050; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Dual-target fluoroquinolone inhibiting both DNA gyrase and topoisomerase IV with similar potency, reducing resistance development.
Cats: FDA-approved for skin infections and wounds. Dogs: approved in some markets. Enhanced anaerobic coverage compared to older fluoroquinolones. Avoid in growing animals.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 5–10 mg/kg | q24h | Strong | Dowers KL, Tasker S, Radecki SV, Lappin MR. Use of pradofloxacin to treat experimentally induced Mycoplasma hemofelis infection in cats. Am J Vet Res. 2009;70(1):105-111. doi:10.2460/ajvr.70.1.105 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1077 (2026-08-01). — Plumb's 10th ed (held) printed p.1050, Pradofloxacin monograph spanning p.1048-1050; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Dog (Domestic) | PO | 3–5 mg/kg | q24h | Moderate |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
| Boothe DM, Bush KM, Boothe HW et al. (2018). Pharmacokinetics and pharmacodynamics of oral pradofloxacin administration in dogs. American Journal of Veterinary Research 79, 1268-1276 doi:10.2460/ajvr.80.5.504 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.352 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.352' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.336; verified by finding the drug named there. If you are holding the book, turn to p.336. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |