ExoticRx · exoticrx.com/drugs/prostaglandin-e2-dinoprostone
US brand names:Prepidil, Cervidil
Prostaglandin E2 (Dinoprostone) is dosed at 0.01–0.02 mg/kg Intravaginal Single application in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Prostaglandin E2 analog that ripens the cervix and stimulates uterine contractions. Promotes cervical dilation for obstetric use.
Use with caution — may cause uterine hyperstimulation. Monitor fetal/neonatal viability. Avoid in cases of uterine scarring.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.