ExoticRx · exoticrx.com/drugs/rasburicase
US brand names:Elitek, Fasturtec
Rasburicase is dosed at 0.05–0.2 mg/kg IV Single dose, may repeat q24h x 1-3 days in dogs, per JVIM Case Reports; Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Recombinant urate oxidase that catalyzes oxidation of uric acid to allantoin, a highly soluble metabolite easily excreted renally.
Anaphylaxis risk — monitor during infusion. Contraindicated in G6PD-deficient animals. Extremely expensive. Destroys uric acid in blood samples.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.05–0.2 mg/kg | Single dose, may repeat q24h x 1-3 days | Weak | JVIM Case Reports; Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.