ExoticRx · exoticrx.com/drugs/romifidine
US brand names:Sedivet
Romifidine is dosed at 0.001–0.04 mg/kg IV Single dose in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.1129, Romifidine monograph spanning p.1129-1130. — Plumb's 10th ed, Romifidine monograph, printed p.1129-1130. — Plumb's 10th ed printed p.1130, Romifidine monograph. Verify against current literature before clinical use.
Alpha-2 adrenergic agonist causing sedation, analgesia, and muscle relaxation. Less ataxia than xylazine and detomidine. Primarily equine use.
Primarily equine. Bradycardia, initial hypertension then hypotension. Reversible with atipamezole. Second-degree AV block common.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.001–0.04 mg/kg | Single dose | Extrapolated | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.1129, Romifidine monograph spanning p.1129-1130. — Plumb's 10th ed, Romifidine monograph, printed p.1129-1130. — Plumb's 10th ed printed p.1130, Romifidine monograph.Compilation only — we have not located an independent source that prints this figure. |
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