ExoticRx · exoticrx.com/drugs/romifidine
US brand names:Sedivet
Romifidine is dosed at 0.02–0.04 mg/kg IV Single dose in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Alpha-2 adrenergic agonist causing sedation, analgesia, and muscle relaxation. Less ataxia than xylazine and detomidine. Primarily equine use.
Primarily equine. Bradycardia, initial hypertension then hypotension. Reversible with atipamezole. Second-degree AV block common.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | IV | 0.02–0.04 mg/kg | Single dose | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | IV | 0.02–0.04 mg/kg | Single dose | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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