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Silymarin for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Silymarin is used in cat for Hepatoprotection, Hepatoprotection, liver disease support. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 2 cited dose rules for Silymarin in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Marin, Milk Thistle, Denamarin, Milk Thistle (Silymarin)

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO5–10 mg/kgq24hLong-termHepatoprotectionModeratePlumb's Veterinary Drug Handbook, 9th Ed
PO5–15 mg/kgq24hLong-term for chronic liver diseaseHepatoprotection, liver disease supportWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Antioxidant and anti-inflammatory flavonoid from milk thistle. Stabilizes hepatocyte membranes, stimulates protein synthesis, and scavenges free radicals.

Side effects & warnings

Generally safe. Often combined with SAMe (Denamarin). Evidence for hepatoprotection moderate. GI upset at high doses. May interact with P-glycoprotein substrates.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Gastrointestinal drugs with cat dosing

AlosetronAminopentamideBalsalazideBudesonide OralCapromorelinCholestyramineCimetidineCisaprideDenamarinDicyclomineDiphenoxylate-AtropineDocusate Sodium

Silymarin dosing in other species

African Grey ParrotDogRabbit
See all species for SilymarinSee all drugs for Cat

Why a species-specific page? Silymarin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.