Cat · Felis catus · typical adult weight 2.50–7.00 kg
Silymarin is dosed at 5–15 mg/kg PO q24h in cats, per Papich MG. Saunders Handbook of Veterinary Drugs, Silymarin monograph, printed p.728 (corpus PDF p.756) — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Silymarin is used in cats for Hepatoprotection, liver disease support. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Silymarin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Marin, Milk Thistle, Denamarin, Milk Thistle (Silymarin)
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–15 mg/kg | q24h | Long-term for chronic liver disease | Hepatoprotection, liver disease support | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, Silymarin monograph, printed p.728 (corpus PDF p.756) — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 30 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.756 | mum of 30 mg/kg PO per day. |
| 5–15 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.756 | • 5-15 mg/kg PO once daily. Some sources recommend a higher dose of a mini- |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Antioxidant and anti-inflammatory flavonoid from milk thistle. Stabilizes hepatocyte membranes, stimulates protein synthesis, and scavenges free radicals.
Generally safe. Often combined with SAMe (Denamarin). Evidence for hepatoprotection moderate. GI upset at high doses. May interact with P-glycoprotein substrates.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Silymarin dose range in cats, with cited source references: PO 5–15 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Silymarin in cats: PO.
Cited course lengths for Silymarin in cats include: Long-term for chronic liver disease. Duration depends on the indication — match it to the specific dose rule in the table above.
Silymarin is indicated in cats for: Hepatoprotection, liver disease support.
These are general warnings for Silymarin across species; consult the cat dosing table above for species-specific guidance. Generally safe. Often combined with SAMe (Denamarin). Evidence for hepatoprotection moderate. GI upset at high doses. May interact with P-glycoprotein substrates.
Why a species-specific page? Silymarin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.