ExoticRx · exoticrx.com/drugs/streptomycin
US brand names:Streptomycin Sulfate
Streptomycin is dosed at 10–20 mg/kg IM q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Irreversibly binds 30S ribosomal subunit. First aminoglycoside discovered. Bactericidal concentration-dependent activity.
Nephrotoxic and ototoxic (vestibular > auditory). Cats highly sensitive. Often used in combination with penicillin for synergy.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 10–20 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.