ExoticRx · exoticrx.com/drugs/triamterene
US brand names:Dyrenium
Triamterene is dosed at 1–2 mg/kg PO q12h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1301 (2026-08-01).. Verify against current literature before clinical use.
Blocks epithelial sodium channels (ENaC) in the collecting duct independently of aldosterone, reducing sodium reabsorption while sparing potassium.
Hyperkalemia risk — monitor electrolytes. Avoid with ACE inhibitors or other K-sparing agents without careful monitoring. Nephrolithiasis risk.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q12h | Weak | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1301 (2026-08-01). |
| Cat (Domestic) | PO | 1–2 mg/kg | q12-24h | Extrapolated | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.837 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.