ExoticRx · exoticrx.com/drugs/trifluridine-ophthalmic
US brand names:Viroptic
Incorporated into viral DNA inhibiting thymidylate synthetase and viral DNA polymerase. Active against HSV-1, HSV-2, and some adenoviruses.
Ophthalmic use only. Local irritation and stinging. Punctal plugging may enhance effect. Commonly used in cats for FHV-1 keratitis.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | Ophthalmic | Gold standard topical antiviral for feline herpes keratitis | q4-6h initially, then q8h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | Ophthalmic | Less commonly used in dogs | q4-6h initially, then q8h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.