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Aminopentamide for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Aminopentamide is used in cat for GI smooth muscle spasm, vomiting. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Aminopentamide in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Centrine

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.01–0.03 mg/kgq8-12hAs needed; short-term use preferredGI smooth muscle spasm, vomitingModeratePlumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database

Absolute dose ceiling, regardless of body weight: 0.2 mg total (PO).

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Mechanism of action

Anticholinergic (parasympatholytic) agent that reduces GI smooth muscle spasm by blocking muscarinic acetylcholine receptors in the GI tract, decreasing motility and secretions.

Side effects & warnings

May cause anticholinergic side effects: dry mouth, urinary retention, tachycardia, mydriasis. Contraindicated in GI obstruction and glaucoma. Use cautiously in patients with cardiac disease.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Gastrointestinal drugs with cat dosing

Aminopentamide dosing in other species

Why a species-specific page? Aminopentamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.