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Bleomycin for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Bleomycin is used in cat for Squamous cell carcinoma (nasal planum, pinnae). Routes documented in cat: Intralesional. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Bleomycin in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Blenoxane

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
Intralesional0.5–1 mg/kgIntralesional injection q1-2 weeks4-6 treatments; assess responseSquamous cell carcinoma (nasal planum, pinnae)ModerateWithrow & MacEwen's Small Animal Clinical Oncology, 6th Ed

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Mechanism of action

Generates free radicals that cause DNA strand breaks and inhibit DNA synthesis. Cell cycle specific for G2 and M phases. Concentrated in skin and lung tissue.

Side effects & warnings

Pulmonary fibrosis is dose-limiting and potentially fatal. Cumulative dose limit. Anaphylaxis risk — test dose recommended. Intralesional use for squamous cell carcinoma in cats.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Oncology drugs with cat dosing

Bleomycin dosing in other species

Why a species-specific page? Bleomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.