Cat · Felis catus · typical adult weight 2.50–7.00 kg
Hydroxyurea is dosed at 25 mg/kg PO 3 times weekly (q48-72h) in cats, per BSAVA Small Animal Formulary 10th Ed, Part A (Canine and Feline), Hydroxycarbamide (Hydroxyurea), DOSES - Cats, corpus p.215 (printed p.199) — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705. Hydroxyurea is used in cats for Myeloproliferative disease / polycythemia vera. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Hydroxyurea in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Hydrea, Droxia
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 25 mg/kg | 3 times weekly (q48-72h) | Chronic use; intensive CBC monitoring | Myeloproliferative disease / polycythemia vera | Weak | BSAVA Small Animal Formulary 10th Ed, Part A (Canine and Feline), Hydroxycarbamide (Hydroxyurea), DOSES - Cats, corpus p.215 (printed p.199) — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 50 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.415 | • 50 mg/kg PO once daily, 3 days/ • 25 mg/kg PO once daily, 3 days/ |
| 25 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.415 | • 50 mg/kg PO once daily, 3 days/ • 25 mg/kg PO once daily, 3 days/ |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits ribonucleotide reductase, blocking conversion of ribonucleotides to deoxyribonucleotides. S-phase specific. Reduces elevated cell counts rapidly.
Myelosuppression is dose-dependent and predictable. Monitor CBC weekly initially. Megaloblastic changes expected. Used for polycythemia vera, CML, and meningioma in dogs and cats.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Hydroxyurea dose range in cats, with cited source references: PO 25 mg/kg 3 times weekly (q48-72h). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Hydroxyurea in cats: PO.
Cited course lengths for Hydroxyurea in cats include: Chronic use; intensive CBC monitoring. Duration depends on the indication — match it to the specific dose rule in the table above.
Hydroxyurea is indicated in cats for: Myeloproliferative disease / polycythemia vera.
These are general warnings for Hydroxyurea across species; consult the cat dosing table above for species-specific guidance. Myelosuppression is dose-dependent and predictable. Monitor CBC weekly initially. Megaloblastic changes expected. Used for polycythemia vera, CML, and meningioma in dogs and cats.
Why a species-specific page? Hydroxyurea pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.