Cat · Felis catus · typical adult weight 2.50–7.00 kg
Vincristine is dosed at 0.5 mg/m2 IV Weekly per protocol in cats, per Plumb's 10th ed printed p.1304, Vincristine monograph spanning p.1304-1306. Vincristine is used in cats for Lymphoma. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Vincristine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Oncovin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.5 mg/m2 | Weekly per protocol | Per protocol | Lymphoma | Moderate | Plumb's 10th ed printed p.1304, Vincristine monograph spanning p.1304-1306.Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.02 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.441 | 0.02 mg/kg i.v. once (limited reports of the use of vincristine to raise circulating plat |
| 0.025–0.05 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.869 | • Antitumor: 0.5-0.75 mg/m2 IV (or 0.025-0.05 mg/kg) once/week. |
| 0.02 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.869 | • Thrombocytopenia: 0.02 mg/kg IV once/week (with prednisolone). |
| Dose (mg/m2) | Route | Source | As printed |
|---|---|---|---|
| 0.5–0.75 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.869 | • Antitumor: 0.5-0.75 mg/m2 IV (or 0.025-0.05 mg/kg) once/week. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
Enter your cat's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Binds tubulin, inhibiting microtubule assembly and arresting cell division at metaphase. Also stimulates platelet release from megakaryocytes.
VESICANT — perivascular extravasation causes severe tissue necrosis. Administer only IV (never IM or SC). Myelosuppression (nadir 4-7 days). Peripheral neuropathy. Also used to treat immune-mediated thrombocytopenia (platelet stimulation).
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vincristine dose range in cats, with cited source references: IV 0.5 mg/m2 Weekly per protocol. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vincristine in cats: IV.
Cited course lengths for Vincristine in cats include: Per protocol. Duration depends on the indication — match it to the specific dose rule in the table above.
Vincristine is indicated in cats for: Lymphoma.
These are general warnings for Vincristine across species; consult the cat dosing table above for species-specific guidance. VESICANT — perivascular extravasation causes severe tissue necrosis. Administer only IV (never IM or SC). Myelosuppression (nadir 4-7 days). Peripheral neuropathy. Also used to treat immune-mediated thrombocytopenia (platelet stimulation).
Why a species-specific page? Vincristine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.