Cat · Felis catus · typical adult weight 2.50–7.00 kg
Doxorubicin is used in cat for Lymphoma, mammary carcinoma. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Doxorubicin in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Adriamycin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1 mg/kg | q21d | 4-6 cycles | Lymphoma, mammary carcinoma | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Intercalates DNA, inhibits topoisomerase II, and generates free radicals. Multiple mechanisms of cytotoxicity against rapidly dividing cells.
VESICANT — extravasation causes severe tissue necrosis (apply cold, dexrazoxane if available). Cumulative cardiotoxicity (max lifetime dose ~240mg/m2 in dogs). Myelosuppression. Anaphylaxis risk in dogs (premedicate with antihistamine). Cats: nephrotoxic.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Doxorubicin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.