ExoticRx · exoticrx.com/drugs/hydroxyurea
Hydrea, Droxia
Inhibits ribonucleotide reductase, blocking conversion of ribonucleotides to deoxyribonucleotides. S-phase specific. Reduces elevated cell counts rapidly.
Myelosuppression is dose-dependent and predictable. Monitor CBC weekly initially. Megaloblastic changes expected. Used for polycythemia vera, CML, and meningioma in dogs and cats.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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