Question 1

What is Cefotaxime used for?

Accepted Answer

Cefotaxime is indicated for: meningitis, Severe infections.

Question 2

What routes can Cefotaxime be administered by?

Accepted Answer

Available routes: IV, IM.

Question 3

Which species have cited Cefotaxime dosing data?

Accepted Answer

Cefotaxime dosing in the ExoticRx formulary covers 6 species: African Grey Parrot, Ball Python, Cat (Domestic), Dog (Domestic), Guinea Pig, Rabbit (Domestic).

Question 4

Is Cefotaxime a controlled substance?

Accepted Answer

Cefotaxime is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Cefotaxime?

Accepted Answer

Good CNS penetration for meningitis. May cause pain at injection site. Adjust dose in renal failure.

Question 6

What are the side effects of Cefotaxime?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Cefotaxime: Good CNS penetration for meningitis. May cause pain at injection site. Adjust dose in renal failure.

Question 7

How does Cefotaxime work?

Accepted Answer

Third-generation cephalosporin with broad gram-negative activity including CNS penetration. Active metabolite (desacetylcefotaxime) provides additional activity.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	25–50 mg/kg	q6-8h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	IV	20–40 mg/kg	q6-8h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Cefotaxime

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Cefotaxime dosing data (6 dose rules)

Evidence levels across 6 dose rules

Backed by 2 published sources

Sample dosing (2 of 6 cited rules)

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