ExoticRx · exoticrx.com/drugs/cyclosporine-ophthalmic-0-05
US brand names:Restasis, Optimmune, Ciclosporin Ophthalmic
Also known as: Ciclosporin Ophthalmic
Cyclosporine Ophthalmic 0.05% is dosed at 0.2 % ointment, 1/4 inch strip per eye Ophthalmic q12h long-term; q24h only w/ caution in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1357, Cyclosporine Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Cyclosporine Ophthalmic monograph, printed p.1357; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Calcineurin inhibitor that suppresses T-cell mediated inflammation in the lacrimal gland. Increases tear production by reducing immune-mediated destruction of lacrimal tissue.
Standard of care for canine keratoconjunctivitis sicca. May take 4-6 weeks for full effect. Transient stinging on application. Also available as 0.2% veterinary formulation (Optimmune).
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 0.2 % ointment, 1/4 inch strip per eye | q12h long-term; q24h only w/ caution | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1357, Cyclosporine Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Cyclosporine Ophthalmic monograph, printed p.1357; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.