Skip to main content

Cyclosporine Ophthalmic 0.05%

Restasis, Optimmune, Ciclosporin Ophthalmic

Calculate dosage
Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Ophthalmic

Routes

Ophthalmic

Indications

dry eyeEosinophilic keratitisKCS (dry eye)Keratoconjunctivitis sicca (KCS)

Mechanism of Action

Calcineurin inhibitor that suppresses T-cell mediated inflammation in the lacrimal gland. Increases tear production by reducing immune-mediated destruction of lacrimal tissue.

Side effects & warnings

Standard of care for canine keratoconjunctivitis sicca. May take 4-6 weeks for full effect. Transient stinging on application. Also available as 0.2% veterinary formulation (Optimmune).

Species with Cyclosporine Ophthalmic 0.05% dosing data (3 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 3 dose rules

Strong×2Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

  • · Gelatt KN, Veterinary Ophthalmology, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 3 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Ophthalmic0 mg/kg1 drop affected eye(s) q12hStrongGelatt KN, Veterinary Ophthalmology, 6th Ed
Cat (Domestic)Ophthalmic0 mg/kg1 drop affected eye(s) q12hModerateGelatt KN, Veterinary Ophthalmology, 6th Ed

Upgrade for Full Details

Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.

View Plans

More Ophthalmic drugs

Calculate Dosage for Cyclosporine Ophthalmic 0.05%