ExoticRx · exoticrx.com/drugs/cyclosporine-ophthalmic-0-05
US brand names:Restasis, Optimmune, Ciclosporin Ophthalmic
Also known as: Ciclosporin Ophthalmic
Cyclosporine Ophthalmic 0.05% is dosed at 0.2 % ointment, 1/4 inch strip per eye Ophthalmic q12h long-term; q24h only w/ caution in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.1357, Cyclosporine Ophthalmic monograph. — Plumb's 10th ed, Cyclosporine Ophthalmic monograph, printed p.1357. Verify against current literature before clinical use.
Calcineurin inhibitor that suppresses T-cell mediated inflammation in the lacrimal gland. Increases tear production by reducing immune-mediated destruction of lacrimal tissue.
Standard of care for canine keratoconjunctivitis sicca. May take 4-6 weeks for full effect. Transient stinging on application. Also available as 0.2% veterinary formulation (Optimmune).
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 0.2 % ointment, 1/4 inch strip per eye | q12h long-term; q24h only w/ caution | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.1357, Cyclosporine Ophthalmic monograph. — Plumb's 10th ed, Cyclosporine Ophthalmic monograph, printed p.1357.Compilation only — we have not located an independent source that prints this figure. |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.