ExoticRx · exoticrx.com/drugs/hydralazine
US brand names:Apresoline
Hydralazine is dosed at 0.5–2 mg/kg PO q12h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.635 (2026-08-01).. Verify against current literature before clinical use.
Directly relaxes arteriolar smooth muscle via interference with calcium transport, reducing afterload.
Reflex tachycardia common (often used with beta-blocker). Hypotension. Monitor blood pressure. Used for acute mitral regurgitation and aortic insufficiency.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–2 mg/kg | q12h | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.635 (2026-08-01). |
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