Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Hydroxychloroquine Dermatologic is used in dog for Discoid lupus erythematosus, Cutaneous vasculitis. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Hydroxychloroquine Dermatologic in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Plaquenil
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Accumulates in lysosomes, raising pH and interfering with antigen processing. Inhibits toll-like receptor signaling and reduces pro-inflammatory cytokine production.
Retinal toxicity with prolonged use — monitor ophthalmic exams. GI upset common. Very limited veterinary use for discoid lupus and other immune-mediated dermatoses.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Hydroxychloroquine Dermatologic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.