ExoticRx · exoticrx.com/drugs/mesalamine
US brand names:Asacol, Pentasa, Lialda
Mesalamine is dosed at 10–20 mg/kg PO q8-12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Active metabolite of sulfasalazine without the sulfa component. Topical anti-inflammatory on colonic mucosa via PPAR-gamma and NF-kB modulation.
Alternative to sulfasalazine without KCS risk. Used for colitis. Delayed-release formulation targets colon. May cause GI upset paradoxically.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–20 mg/kg | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.