ExoticRx · exoticrx.com/drugs/naftifine
US brand names:Naftin
Inhibits squalene epoxidase blocking ergosterol biosynthesis. Fungicidal against dermatophytes. Also has anti-inflammatory properties.
Topical use only. Local irritation (burning, stinging). First allylamine antifungal developed. Active against dermatophytes.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | Topical | Topical use | q12-24h | Weak | Gupta AK, et al: Antifungal agents: An overview: Part I. J Am Acad Dermatol 30:677, 1994. doi:10.1016/s0190-9622(08)81495-8 — Verified against Muller & Kirk's Small Animal Dermatology, 7th Ed, p.238 (2026-08-01). |
| Dog (Domestic) | Topical | Topical allylamine | q12-24h | Weak | Gupta AK, et al: Antifungal agents: An overview: Part I. J Am Acad Dermatol 30:677, 1994. doi:10.1016/s0190-9622(08)81495-8 — Verified against Muller & Kirk's Small Animal Dermatology, 7th Ed, p.238 (2026-08-01). |
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