ExoticRx · exoticrx.com/drugs/octreotide
US brand names:Sandostatin
Octreotide is dosed at 0.01–0.04 mg/kg SC q8-12h in dogs, per Goutal CM, Brugmann BL, Ryan KA. Insulinoma in Dogs: A Review. J Am Anim Hosp Assoc. 2012;48(3):151-163. doi:10.5326/jaaha-ms-5745 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.978 (2026-08-01). — Plumb's 10th ed (held) printed p.950, Octreotide monograph spanning p.950-951; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Long-acting somatostatin analogue that inhibits GH, insulin, glucagon, and GI peptide secretion. Reduces splanchnic blood flow and GI motility.
May cause hyperglycemia or hypoglycemia. GI side effects common. Used for insulinoma, gastrinoma, and variceal bleeding in veterinary medicine.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 0.01–0.04 mg/kg | q8-12h | Moderate | Goutal CM, Brugmann BL, Ryan KA. Insulinoma in Dogs: A Review. J Am Anim Hosp Assoc. 2012;48(3):151-163. doi:10.5326/jaaha-ms-5745 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.978 (2026-08-01). — Plumb's 10th ed (held) printed p.950, Octreotide monograph spanning p.950-951; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | SC | 0.01 mg/kg | q8-12h | Weak |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.