Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pioglitazone is dosed at 0.5–3 mg/kg PO q24h in dogs, per Source not established. The citation previously shown here named no retrievable document; a literature search on 2026-07-31 found no source that states this dose for this species and route. Treat as unverified and confirm against a primary reference before clinical use.. Pioglitazone is used in dogs for Insulin-resistant diabetes (adjunct). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pioglitazone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Actos
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–3 mg/kg | q24h | Long-term adjunct; monitor liver enzymes monthly initially | Insulin-resistant diabetes (adjunct) | Weak | Source not established. The citation previously shown here named no retrievable document; a literature search on 2026-07-31 found no source that states this dose for this species and route. Treat as unverified and confirm against a primary reference before clinical use. |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
PPARgamma agonist that improves insulin sensitivity in peripheral tissues by enhancing adipocyte differentiation and glucose transporter expression.
Hepatotoxicity risk — monitor liver enzymes. Weight gain and fluid retention. Limited veterinary use — investigational for insulin-resistant diabetic cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pioglitazone dose range in dogs, with cited source references: PO 0.5–3 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pioglitazone in dogs: PO.
Cited course lengths for Pioglitazone in dogs include: Long-term adjunct; monitor liver enzymes monthly initially. Duration depends on the indication — match it to the specific dose rule in the table above.
Pioglitazone is indicated in dogs for: Insulin-resistant diabetes (adjunct).
These are general warnings for Pioglitazone across species; consult the dog dosing table above for species-specific guidance. Hepatotoxicity risk — monitor liver enzymes. Weight gain and fluid retention. Limited veterinary use — investigational for insulin-resistant diabetic cats.
Why a species-specific page? Pioglitazone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.