ExoticRx · exoticrx.com/drugs/potassium-iodide-antifungal
US brand names:SSKI
Potassium Iodide (Antifungal) is dosed at 20–40 mg/kg PO q8-12h in dogs, per Muller & Kirk's Small Animal Dermatology, 7th ed (2013), IODIDES monograph, p.230 (corpus p.242). Corroborating: Papich Handbook of Veterinary Drugs, 4th ed (2016), Potassium Iodide, p.659 (corpus 687), 'Dogs and Cats - Fungal infections: start with 5 mg/kg q8h PO and increase gradually to 25 mg/kg q8h PO' (same text also at Iodide monograph p.404).. Verify against current literature before clinical use.
Mechanism not fully understood. Enhances neutrophil killing of fungi. Effective specifically for sporotrichosis (lymphocutaneous form).
GI upset. Iodism (metallic taste, nasal congestion, skin rash). Cats are very sensitive — start at low doses. Contraindicated in hyperthyroidism.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 20–40 mg/kg | q8-12h | Strong | Muller & Kirk's Small Animal Dermatology, 7th ed (2013), IODIDES monograph, p.230 (corpus p.242). Corroborating: Papich Handbook of Veterinary Drugs, 4th ed (2016), Potassium Iodide, p.659 (corpus 687), 'Dogs and Cats - Fungal infections: start with 5 mg/kg q8h PO and increase gradually to 25 mg/kg q8h PO' (same text also at Iodide monograph p.404). |
| Cat (Domestic) | PO | 20 mg/kg | q12-24h | Moderate | Muller & Kirk's Small Animal Dermatology, 7th ed (2013), IODIDES monograph, p.230 (corpus p.242). Same monograph, ADDITIONAL INFORMATION: 'cats are given 10 to 20 mg/kg every 12 hours to every 24 hours with food'. Second appearance: same book p.213 (corpus 225), 'Sodium iodide (40 mg/kg (dog) 20 mg/kg (cat) orally every 12 hours)'. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.